2005 Program
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2005 Participant: Matthew Simone
 


Project Title:
Treating Thin Film Surfaces with NanoIndentation to Control Spacing of Mimicked Adhesion Sites

Faculty Advisor:
Brian Helmke

(Left) Working at the clean-hood,
Matthew changes the liquid medium
to provide additional nutrients for
endothelial cell-growth.

 

Project Summary:

Using Gold nanodots on an Aluminum Oxide Thin Film, I will be using Nanoindentation to control the size of the dots and their spacing on the surface of the thin film. This surface is used to represent endothelial tissue in the heart. A study of the rolling kinetics of leukocyte (white blood cells) can be studied and documented. Eventually the surface could be used as a diagnostic tool for leukocyte defect disorders including leukemia and other cancers.

(Right) Changing pipettes
during the replacement of
the nutrient medium.


 
 
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